Alzheimer’s disease (AD), Type 2 Diabetes (TSD), exercise, MIND diet, DASH diet, Mediterranean diet, Okinawan diet, metformin, pioglitazone, insulin


Medicine and Health Sciences


Alzheimer’s Disease (AD) and Type 2 Diabetes (T2D) are chronic conditions increasing in prevalence that impact the daily lives of those afflicted with them. AD and T2D are linked through the pathophysiology of insulin resistance. Thus, there are intersections that can allow the management of T2D to improve the treatment and prevention of AD. Modifiable risk factors, such as diet and physical activity level, play important roles in the health of T2D patients as well as in preventing AD. Medications traditionally used in the treatment of T2D, such as metformin, pioglitazone, and insulin, are being examined for use in the new context of treating AD. Improving patient education on chronic diseases and modifiable risk factors, as well as continuing research into applications of drugs to treat and prevent AD, can reduce much of the suffering associated with AD and other chronic illnesses, such as T2D.


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