Graduate Degree Type
Medical Dosimetry (M.S.)
This study aims to investigate the comparisons in dynamic conformal arc, VMAT (no ASC), forced MU limitations (ASC), or a 50/50 hybrid arc (ASC) in how they can improve a lung SBRT case where the tumor is abutting a dose critical structure. The goal of this research is to investigate multiple treatment techniques in an attempt to increase the dose constraint pass rate. The variables in comparison are how well different plan iterations can successfully meet constraints as well as pass a 0.5 modulation complexity score (MCS).
10 previously treated patients were used in this study who exhibited tumors abutting the heart, great vessels, bronchus, brachial plexus, rib, and the spinal cord. All of these patients were planned in all 5 iterations. Each of the plan consisted of two partial arcs and the patient specific iterations were compared with the same gantry arcs.
The dynamic conformal arc plan exhibited the highest MCS, however it also was unable to pass any of the constraints. The VMAT plan iteration failed the MCS parameter on every patient, however more plans were able to meet the dose constraints. With an introduction of a x1 MU forced limitation, x1.5MU forced limitation, and a 50/50 hybrid, MCS as well as dose constraint pass rate significantly improved. The 50/50 hybrid iteration exhibited the most plans that passed both of the constraint variables. This treatment method incorporates the dose conformality of a dynamic conformal arc with the dose painting abilities of a VMAT arc. The ASC that was applied to these beams prevents the beam from becoming overly modulated which would result in an increase in MU and an increase in low dose to the patient.
This study has been able to determine that a 50/50 hybrid technique or a VMAT (ASC) with a forced MU limitation can be considered a reliable and reproducible alternative for treating lung SBRT cases that abut a dose limiting organ.
Loutos, Shawn, "A Quantitative Investigation of Treating Lung Tumors with Dynamic Conformal Arcs vs. VMAT for Lung SBRT Plans" (2022). Culminating Experience Projects. 189.