Consumption of omega-3 fatty acids benefits the cardiovascular system by reducing blood vessel inflammatory responses. Our recent work showed omega-3 fatty acids decrease connexin 43 (Cx43) expression in cultured endothelial cells after 1 day. Our interest in Cx43 was as marker of inflammation as omega-3 fatty acids are strongly implicated as anti-inflammatory agents. Localized inflammatory responses drive the growth of the atherosclerotic plaques responsible for a majority of cardiovascular diseases. Anything that affects the inflammatory response will affect the growth (and stability which is also important) of those plaques. This poster will summarize current knowledge of atherosclerosis and inflammation as well as the impact of omega-3 fatty acids on inflammation.
Goen, Madison and Morrison, Kyle, "Impact of Cell Density on Cx43 Expression in Endothelial Cells" (2020). Student Scholars Day Posters. 60.