Date Approved


Graduate Degree Type


Degree Name

Nursing (M.S.N.)

Degree Program

College of Nursing


Chemotherapy-induced fatigue is a common side effect for cancer patients. This experimental study attempted to identify the effects of an early nursing intervention designed to facilitate adaptation to chemotherapy-induced fetigue. Roy’s Adaptation Model was the conceptual framework. A convenience sample (n=49) was randomly assigned to experimental (n= 16) and control (n=19) groups. Each group completed the Piper Fatigue Scale (PFS) during cycle one of chemotherapy. The control group received the standard teaching regarding 6tigue. The experimental group received additional instruction about fatigue. Both groups completed the PFS again during the third chemotherapy cycle (2-3 months later). No significant differences between the two groups were found. Additional analysis found significant differences between pretest and posttest for women (p=.036) but not for men (p=.233) and for the younger group (p=.003) but not the older group (p=.288). Chemotherapy-induced fatigue is a complex phenomenon requiring continued exploration of causes and treatments.


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