Date Approved


Graduate Degree Type


Degree Name

Nursing (M.S.N.)

Degree Program

College of Nursing


There is no significant difference in the relationship between oral or vaginal metronidazole and oral clindamycin in the treatment of bacterial vaginosis (BV) in early pregnancy and the re-occurrence rate of BV at 35 to 37 weeks gestation. Treatment of BV in pregnancy has been shown to decrease the preterm delivery rate saving millions of dollars and improving the health of infants. This was a descriptive, correlational study using a retrospective chart review. A constructed checklist was used for collecting data from 186 charts.

Age, parity, and insurance were comparable in each of the three drug groups. The re-occurrence rate of BV when tested in the third trimester showed no significant differences in comparison of the three drug treatment groups (Chi-square = .55; df = 2; p = .76). All three drugs were equally effective in the treatment of BV.


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