Date Approved


Graduate Degree Type


Degree Name

Physician Assistant Studies (M.P.A.S.)

Degree Program

Physician Assistant Studies


The objective of this study was to determine the frequency of myocardial infarctions in coronary arteries with previously non-significant (<50%) stenosis identified on coronary angiography. The angiograms of ten subjects who had undergone cardiac catheterization prior to their acute myocardial infarction were evaluated. Six of the ten subjects (60%) were found to have an acute myocardial infarction in areas supplied by vessels with <50% stenosis identified on previous angiography. Three of these six subjects had underwent percutaneous transluminal coronary angioplasty (PTCA) after angiography and one subject undergone coronary artery bypass grafting (CABG) prior to the initial angiogram. Four of the ten subjects (40%) included those who had >50% stenosis identified on prior angiography in the infarct related artery. Although this study involved a small sample that did not yield statistically significant results, the data did point to the fact that an acute myocardial infarction can occur in vessels with non-significant (<50%) stenosis.


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