Date Approved


Graduate Degree Type


Degree Name

Physical Therapy (M.S.)

Degree Program

Physical Therapy


Nutritional Supplementation of glucosamine sulfate and chondroitin sulfate are being promoted in the treatment of osteoarthritis. Recent research has indicated that gelatin was found effective. Moderate exercise is also being advocated. The purpose of this eight week double blind study was to examine the effects of the inexpensive nutritional supplement gelatin, in the form of Knox Nutrajoint, and exercise on pain and functional activity in 49 subjects with osteoarthritis in one or both knees. Subjects were randomly assigned to one of four groups: placebo, placebo plus exercise, gelatin supplement plus exercise and exercise. Exercise consisted of a progressive walking program. Results were assessed via ANOVA and ANCOVA. No significant difference (p<.05) was found for any group on perceived functional ability or pain as measured by the Arthritis Index Measurement Tool. Both exercise groups did show a significant improvement in mood level. The result of this study could not support the use of gelatin supplementation or a non supervised walking program for the treatment of OA.


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