Faculty Scholarly Dissemination Grants

Title

Circulating microRNAs in Plasma as Predictive Biomarkers for Parkinson's Disease: a New Paradigm

Department

Cell and Molecular Biology

College

College of Liberal Arts and Sciences

Disciplines

Life Sciences

Abstract

Parkinsons disease (PD) is a complex neurological disorder caused by progressive loss of dopaminergic neurons, leading to motor, cognitive, and gastro-intestinal dysfunctions. Due to the subtle nature of its motor symptoms which current clinical diagnosis is majorly based on, neurodegeneration has reached a relatively advanced stage by the time of diagnosis. Here, we identify and develop a panel of circulating microRNA (miRNAs) in plasma as biomarkers for PD. The biomarkers achieve the predictive power of 91% sensitivity and 100% specificity.

Conference Name

10th Annual microRNA as Biomarkers and Diagnostics

Conference Location

Boston, MA

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