Event Title

Cross-talk Between Alzheimer's and Parkinson's Disease: Evaluation of microRNA Expressions

Location

Hager-Lubbers Exhibition Hall

Start Date

15-4-2015 3:30 PM

Description

Alzheimer's disease (AD) is the most common neurodegenerative disease followed by Parkinson’s disease (PD). There is no cure for AD or PD and definitive diagnosis of these devastating diseases is achieved by autopsy. Although AD and PD are distinct clinical conditions, emerging evidence has shown pathological similarities between these two disorders, such as cognitive impairment and aggregation of misfolded proteins, suggests cross­disease association. MicroRNAs (miRNAs) are a class of small, non­coding RNA molecules that are involved in many essential biological processes such as cell development and differentiation. Recently, miRNAs have been found to distinguished PD patients from neurologically healthy controls. In this project, we investigate the gene expression of PD­related miRNAs on AD brain samples to shed light on the similarity between AD and PD.

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Apr 15th, 3:30 PM

Cross-talk Between Alzheimer's and Parkinson's Disease: Evaluation of microRNA Expressions

Hager-Lubbers Exhibition Hall

Alzheimer's disease (AD) is the most common neurodegenerative disease followed by Parkinson’s disease (PD). There is no cure for AD or PD and definitive diagnosis of these devastating diseases is achieved by autopsy. Although AD and PD are distinct clinical conditions, emerging evidence has shown pathological similarities between these two disorders, such as cognitive impairment and aggregation of misfolded proteins, suggests cross­disease association. MicroRNAs (miRNAs) are a class of small, non­coding RNA molecules that are involved in many essential biological processes such as cell development and differentiation. Recently, miRNAs have been found to distinguished PD patients from neurologically healthy controls. In this project, we investigate the gene expression of PD­related miRNAs on AD brain samples to shed light on the similarity between AD and PD.