Cross-talk Between Alzheimer's and Parkinson's Disease: Evaluation of microRNA Expressions
Location
Hager-Lubbers Exhibition Hall
Description
Alzheimer's disease (AD) is the most common neurodegenerative disease followed by Parkinson’s disease (PD). There is no cure for AD or PD and definitive diagnosis of these devastating diseases is achieved by autopsy. Although AD and PD are distinct clinical conditions, emerging evidence has shown pathological similarities between these two disorders, such as cognitive impairment and aggregation of misfolded proteins, suggests crossdisease association. MicroRNAs (miRNAs) are a class of small, noncoding RNA molecules that are involved in many essential biological processes such as cell development and differentiation. Recently, miRNAs have been found to distinguished PD patients from neurologically healthy controls. In this project, we investigate the gene expression of PDrelated miRNAs on AD brain samples to shed light on the similarity between AD and PD.
Cross-talk Between Alzheimer's and Parkinson's Disease: Evaluation of microRNA Expressions
Hager-Lubbers Exhibition Hall
Alzheimer's disease (AD) is the most common neurodegenerative disease followed by Parkinson’s disease (PD). There is no cure for AD or PD and definitive diagnosis of these devastating diseases is achieved by autopsy. Although AD and PD are distinct clinical conditions, emerging evidence has shown pathological similarities between these two disorders, such as cognitive impairment and aggregation of misfolded proteins, suggests crossdisease association. MicroRNAs (miRNAs) are a class of small, noncoding RNA molecules that are involved in many essential biological processes such as cell development and differentiation. Recently, miRNAs have been found to distinguished PD patients from neurologically healthy controls. In this project, we investigate the gene expression of PDrelated miRNAs on AD brain samples to shed light on the similarity between AD and PD.