Date Approved


Graduate Degree Type


Degree Name

Nursing (M.S.N.)

Degree Program

College of Nursing

First Advisor

Andrea C. Bostrom

Second Advisor

Louette R. Lutjens

Third Advisor

Theresa Bacon-Baguley


Although the need for heparin in flush solutions has not been established, the currently accepted standard of practice is to use heparinized solutions in arterial catheter flush devices. Exposure to heparin may place patients at risk for developing heparin-induced thrombocytopenia (HITP) and subsequent embolic events. The purpose of the study was to test the null hypothesis that there is no significant difference in patency of arterial catheters maintained with heparinized or non-heparinized normal saline solutions. An experimental design using a convenience sample (N = 31) and random assignment into experimental and control groups was used. There was no statistically significant difference in catheter patency between the two groups. The null hypothesis was supported.


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