Faculty Scholarly Dissemination Grants
Translational Meta-Analysis Tool for Temporal Gene Expression Profiles
Department
School of Computing and Information Systems
College
Padnos College of Engineering and Computing
Date Range
2012-2013
Disciplines
Engineering
Abstract
Widespread use of microarray technology that led to highly complex datasets often is addressing similar or related biological questions. In translational medicine research is often based on measurements that have been obtained at different points in time. However, the researcher looks at them as a progression over time. If a biological stimulus shows an effect on a particular gene that is reversed over time, this would show, for instance, as a peak in the genes temporal expression profile. Our program SPOT helps researchers find these patterns in large sets of microarray data. We created the software tool using open-source platforms and the Semantic Web tool Protégé-OWL. Keywords. Research and education; enhancing biological, clinical and epidemiological research and trials; bioinformatics; translational research.
Conference Name
Medical Informatics Europe MIE 2012
Conference Location
Pisa, Italy
ScholarWorks Citation
Tusch, Guenter and Tole, Olvi, "Translational Meta-Analysis Tool for Temporal Gene Expression Profiles" (2013). Faculty Scholarly Dissemination Grants. 1030.
https://scholarworks.gvsu.edu/fsdg/1030
