Faculty Scholarly Dissemination Grants
Facile Synthesis of Arylsulfonates and Exploration of their Use in Sonogashira and Ullman Cross-Coupling Reactions
Department
Chemistry Department
College
College of Liberal Arts and Sciences
Date Range
2014-2015
Disciplines
Physical Sciences and Mathematics
Abstract
The C-O bond of phenol can be activated by reaction with arylsulfonyl chlorides, to make the corresponding arylsulfonates that can be used in subsequent reactions. Facile synthesis of different arylsulfonates from various arylsulfonyl chlorides and phenol are reported. What is unique about the synthesis is that very good to excellent yields of arylsulfonates were obtained without the use of column chromatography. A more efficient purification technique was developed based on crystallization. Initial experiments are underway to test the different arylsulfonates as alternative substrates for Sonogashira and Ullman cross-coupling reactions.
Conference Name
248th National Meeting of the American Chemical Society
Conference Location
San Francisco, CA
ScholarWorks Citation
Ngassa, Felix; Riley, Sean; Kerr, Stacey; and Atanasova, Lina, "Facile Synthesis of Arylsulfonates and Exploration of their Use in Sonogashira and Ullman Cross-Coupling Reactions" (2015). Faculty Scholarly Dissemination Grants. 495.
https://scholarworks.gvsu.edu/fsdg/495
