Analysis of Outcome Measures in Patients with a Fragility Fracture Treated with Forteo and Supplemented with Prescriptive Vitamin D

Presentation Type

Oral and/or Visual Presentation

Presenter Major(s)

Physician Assistant Studies

Mentor Information

Theresa Bacon-Baguley, bacon-bt@gvsu.edu

Department

Physician Assistant Studies

Location

Kirkhof Center 2201

Start Date

13-4-2011 3:00 PM

End Date

13-4-2011 3:30 PM

Keywords

Health, Illness, and Healing

Abstract

Osteoporosis is defined by the National Osteoporosis Foundation as a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and increased susceptibility to fractures. The cause of osteoporosis is linked to a disorder in the normal bone metabolism. Bone tissue normally undergoes a cyclical process of breakdown (bone resorption) followed by bone formation. Disruption of this cycle can lead to a low bone mineralization and osteoporosis. Both calcium and vitamin D play a crucial role in bone formation. Without sufficient vitamin D levels, calcium cannot be absorbed in the GI tract and bone mineralization decreases. One of the treatments for osteoporosis is Forteo@ (teriparatide). The purpose of this study was to determine the change in bone mineral density and physiologic markers of bone metabolism, in those individuals who were treated with Forteo@ for osteoporosis and were also prescribed vitamin D based on their pretreatment vitamin D levels.

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Apr 13th, 3:00 PM Apr 13th, 3:30 PM

Analysis of Outcome Measures in Patients with a Fragility Fracture Treated with Forteo and Supplemented with Prescriptive Vitamin D

Kirkhof Center 2201

Osteoporosis is defined by the National Osteoporosis Foundation as a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and increased susceptibility to fractures. The cause of osteoporosis is linked to a disorder in the normal bone metabolism. Bone tissue normally undergoes a cyclical process of breakdown (bone resorption) followed by bone formation. Disruption of this cycle can lead to a low bone mineralization and osteoporosis. Both calcium and vitamin D play a crucial role in bone formation. Without sufficient vitamin D levels, calcium cannot be absorbed in the GI tract and bone mineralization decreases. One of the treatments for osteoporosis is Forteo@ (teriparatide). The purpose of this study was to determine the change in bone mineral density and physiologic markers of bone metabolism, in those individuals who were treated with Forteo@ for osteoporosis and were also prescribed vitamin D based on their pretreatment vitamin D levels.