Event Title
Effect of Increased G-Load on Rat Mammary Gland Development
Presentation Type
Poster/Portfolio
Presenter Major(s)
Cell and Molecular Biology
Mentor Information
Osman Patel
Department
Cell and Molecular Biology
Location
Henry Hall Atrium 13
Start Date
11-4-2012 9:00 AM
Keywords
Health, Life Science
Abstract
Mammary gland epithelial differentiation is dependent on an integral cytoskeletal support structure and hormonal direction. The objective of this study was to determine the effects of chronic hypergravity (HG) exposure during pregnancy on abundance of the cellular scaffolding proteins in the rat mammary gland. One group of pregnant rats were exposed to either 2g (HG) or 1g (control) from days 11 to 20 of gestation (G20). Another control (1g) and experimental (2g) groups were investigated from days 11 of pregnancy through days 1 (P1) and 3 (P3) postpartum. On G20, P1 and P3, mammary tissue was collected and processed for immunohistochemical based quantification of proteins (actin, tubulin cytokeratin, vimentin). At G20, and P3 significant (p
Effect of Increased G-Load on Rat Mammary Gland Development
Henry Hall Atrium 13
Mammary gland epithelial differentiation is dependent on an integral cytoskeletal support structure and hormonal direction. The objective of this study was to determine the effects of chronic hypergravity (HG) exposure during pregnancy on abundance of the cellular scaffolding proteins in the rat mammary gland. One group of pregnant rats were exposed to either 2g (HG) or 1g (control) from days 11 to 20 of gestation (G20). Another control (1g) and experimental (2g) groups were investigated from days 11 of pregnancy through days 1 (P1) and 3 (P3) postpartum. On G20, P1 and P3, mammary tissue was collected and processed for immunohistochemical based quantification of proteins (actin, tubulin cytokeratin, vimentin). At G20, and P3 significant (p