Event Title

Effect of Cold Exposure on the Muscle Metaboreflex During L-tyrosine Supplementation

Presentation Type

Poster/Portfolio

Presenter Major(s)

Exercise Science

Mentor Information

James Lang

Department

Movement Science

Location

Henry Hall Atrium 27

Start Date

10-4-2013 1:00 PM

End Date

10-4-2013 2:00 PM

Keywords

Health

Abstract

Significance: The L-tyrosine pool within sympathetic nerve terminals that is available for catecholamine synthesis may limit sympathetic function. After supplementation of L-tyrosine, the sympathetically-mediated vasoconstriction response during cold exposure was increased in aged skin. Purpose: To investigate oral supplementation of 150 mg/kg of L-tyrosine on the metaboreflex-mediated blood pressure response during passive whole body cooling. Protocol: Subjects performed isometric exercise using a handgrip dynamometer for 2 min at 35% maximal voluntary contraction. Five seconds before exercise ended, a blood pressure cuff was inflated to suprasystolic pressure to trap vasoactive metabolites within the forearm for an additional 3 min. The test was then repeated after whole body cooling to a mean skin temperature of 30.5 C. Anticipated Results: Supplementation of L-tyrosine prior to whole-body cooling will result in an increase in the metaboreflex-mediated blood pressure response.

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Apr 10th, 1:00 PM Apr 10th, 2:00 PM

Effect of Cold Exposure on the Muscle Metaboreflex During L-tyrosine Supplementation

Henry Hall Atrium 27

Significance: The L-tyrosine pool within sympathetic nerve terminals that is available for catecholamine synthesis may limit sympathetic function. After supplementation of L-tyrosine, the sympathetically-mediated vasoconstriction response during cold exposure was increased in aged skin. Purpose: To investigate oral supplementation of 150 mg/kg of L-tyrosine on the metaboreflex-mediated blood pressure response during passive whole body cooling. Protocol: Subjects performed isometric exercise using a handgrip dynamometer for 2 min at 35% maximal voluntary contraction. Five seconds before exercise ended, a blood pressure cuff was inflated to suprasystolic pressure to trap vasoactive metabolites within the forearm for an additional 3 min. The test was then repeated after whole body cooling to a mean skin temperature of 30.5 C. Anticipated Results: Supplementation of L-tyrosine prior to whole-body cooling will result in an increase in the metaboreflex-mediated blood pressure response.