"The Organic Synthesis of Anthranilic Acid Derivatives as Potential Act" by Paul Chappell
 

Publication Date

4-2020

First Advisor

Laurie Witucki

Second Advisor

Rod Morgan

Third Advisor

William Schroeder

Abstract

The objective of this research project was to synthesize multiple derivatives of anthranilic acid. These derivatives will then be tested for antibiotic activity against Staphylococcus aureus and Escherichia coli (E. coli). As bacteria become more resistant to penicillin-based antibiotics, the exploration of anthranilic acid-based antibiotics could serve an important role for future medical use. This research project included data collection via 1H-NMR, 12C-NMR, TLC, MP, and IR to determine purity for biological testing.



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