Date Approved

8-5-2024

Graduate Degree Type

Thesis

Degree Name

Engineering (M.S.E.)

Degree Program

School of Engineering

First Advisor

Dr. Brian Krug

Academic Year

2023/2024

Abstract

Fast Scan Cyclic Voltammetry (FSCV) is a widely used electrochemical technique for real-time measurement of the brain’s chemical messengers, including the molecule dopamine, with high temporal resolution. Currently the financial burden of performing FSCV is quite high, ranging from $8,000 to $20,000+ making the barrier to entry nearly insurmountable for laboratories and classrooms at small institutions. The purpose of this project was to develop a Do-It-Yourself (DIY), portable, and cost-effective FSCV system for use in laboratory and classroom settings. The project aimed to create a compact and cost-effective system that could be used by researchers and educators to study dopamine levels and dynamics in various settings. By utilizing a Hercules Launchpad by Texas Instruments, a device was designed to perform FSCV of dopamine. The device was able to successfully produce the required waveform and collect the results. This project offers proof of concept for the use of Pulse Width Modulation (PWM) in the generation of a FSCV triangle waveform for dopamine concentration measurements.

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