Vasodilation and Mega Man Vitapack
Presentation Type
Poster/Portfolio
Presenter Major(s)
Biomedical Sciences, Health Professions
Mentor Information
Francis Sylvester, sylvestf@gvsu.edu
Department
Biomedical Sciences
Location
Henry Hall Atrium 71
Start Date
13-4-2011 10:00 AM
End Date
13-4-2011 11:00 AM
Keywords
Physical Science
Abstract
Vasodilation is a desirable effect for athletes as it increases blood flow to muscles, thus enhancing oxygen delivery. The increased oxygen delivery may minimize the amount of lactic acid present in exercising muscle resulting in a concomitant delay in the onset of fatigue. The effect of the NO component of Mega Man vitamins, a presumed vasodilator, will be studied using a porcine heart model. The anterior interventricular artery will be dissected, cut into small rings, and mounted in an organ bath coupled to a force transducer. Dose responses to potassium chloride (vasoconstrictor) and sodium nitroprusside (vasodilator) will be recorded to assess vessel viability. If viable, the rings will be preconstricted with potassium chloride followed by exposure to increasing concentrations of the “NO†supplement. Results from this study should resolve the validity of the manufacture's claim that Mega Man vitamins include a vasodilator postulated to improve athletic performance.
Vasodilation and Mega Man Vitapack
Henry Hall Atrium 71
Vasodilation is a desirable effect for athletes as it increases blood flow to muscles, thus enhancing oxygen delivery. The increased oxygen delivery may minimize the amount of lactic acid present in exercising muscle resulting in a concomitant delay in the onset of fatigue. The effect of the NO component of Mega Man vitamins, a presumed vasodilator, will be studied using a porcine heart model. The anterior interventricular artery will be dissected, cut into small rings, and mounted in an organ bath coupled to a force transducer. Dose responses to potassium chloride (vasoconstrictor) and sodium nitroprusside (vasodilator) will be recorded to assess vessel viability. If viable, the rings will be preconstricted with potassium chloride followed by exposure to increasing concentrations of the “NO†supplement. Results from this study should resolve the validity of the manufacture's claim that Mega Man vitamins include a vasodilator postulated to improve athletic performance.