Vasodilation and Mega Man Vitapack

Presentation Type

Poster/Portfolio

Presenter Major(s)

Biomedical Sciences, Health Professions

Mentor Information

Francis Sylvester, sylvestf@gvsu.edu

Department

Biomedical Sciences

Location

Henry Hall Atrium 71

Start Date

13-4-2011 10:00 AM

End Date

13-4-2011 11:00 AM

Keywords

Physical Science

Abstract

Vasodilation is a desirable effect for athletes as it increases blood flow to muscles, thus enhancing oxygen delivery. The increased oxygen delivery may minimize the amount of lactic acid present in exercising muscle resulting in a concomitant delay in the onset of fatigue. The effect of the NO component of Mega Man vitamins, a presumed vasodilator, will be studied using a porcine heart model. The anterior interventricular artery will be dissected, cut into small rings, and mounted in an organ bath coupled to a force transducer. Dose responses to potassium chloride (vasoconstrictor) and sodium nitroprusside (vasodilator) will be recorded to assess vessel viability. If viable, the rings will be preconstricted with potassium chloride followed by exposure to increasing concentrations of the “NO” supplement. Results from this study should resolve the validity of the manufacture's claim that Mega Man vitamins include a vasodilator postulated to improve athletic performance.

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Apr 13th, 10:00 AM Apr 13th, 11:00 AM

Vasodilation and Mega Man Vitapack

Henry Hall Atrium 71

Vasodilation is a desirable effect for athletes as it increases blood flow to muscles, thus enhancing oxygen delivery. The increased oxygen delivery may minimize the amount of lactic acid present in exercising muscle resulting in a concomitant delay in the onset of fatigue. The effect of the NO component of Mega Man vitamins, a presumed vasodilator, will be studied using a porcine heart model. The anterior interventricular artery will be dissected, cut into small rings, and mounted in an organ bath coupled to a force transducer. Dose responses to potassium chloride (vasoconstrictor) and sodium nitroprusside (vasodilator) will be recorded to assess vessel viability. If viable, the rings will be preconstricted with potassium chloride followed by exposure to increasing concentrations of the “NO” supplement. Results from this study should resolve the validity of the manufacture's claim that Mega Man vitamins include a vasodilator postulated to improve athletic performance.