Focal Adhesion Kinase: Potential Cancer Inhibitors

Presentation Type

Poster/Portfolio

Presenter Major(s)

Biomedical Sciences

Mentor Information

Laurie Witucki

Department

Chemistry

Location

Kirkhof Center KC51

Start Date

11-4-2012 9:00 AM

Keywords

Health

Abstract

Focal Adhesion Kinase (FAK) is a non-receptor protein kinase that plays a critical role in cell signaling, and the regulation of many cellular processes. FAK is found up regulated in a variety of metastatic cancers, and a key component for cellular migration through the extracellular matrix. FAK acts to disassemble focal adhesions constructed by the cell, enabling the cell to lay down further scaffolding for cellular movement, growth and repair. Over expression of FAK is found to be an important biomarker in invasive metastatic cancers, making this protein a target of interest for development of novel treatments.

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Apr 11th, 9:00 AM

Focal Adhesion Kinase: Potential Cancer Inhibitors

Kirkhof Center KC51

Focal Adhesion Kinase (FAK) is a non-receptor protein kinase that plays a critical role in cell signaling, and the regulation of many cellular processes. FAK is found up regulated in a variety of metastatic cancers, and a key component for cellular migration through the extracellular matrix. FAK acts to disassemble focal adhesions constructed by the cell, enabling the cell to lay down further scaffolding for cellular movement, growth and repair. Over expression of FAK is found to be an important biomarker in invasive metastatic cancers, making this protein a target of interest for development of novel treatments.